494518

Ethyl acetate

biotech. grade, ≥99.8%

• Synonym(s): EtOAc
• Linear Formula: CH₃COOC₂H₅
• CAS Number: 141-78-6
• Molecular Weight: 88.11
• Beilstein: 506104
• EC Number: 205-500-4
• MDL number: MFCD00009171
• UNSPSC Code: 12352108
• PubChem Substance ID: 329757457
• NACRES: NA.01

Properties

• grade: biotech. grade
• vapor density: 3 (20 °C, vs air)
• vapor pressure: 73 mmHg ( 20 °C)
• Assay: ≥99.8%
• form: liquid
• autoignition temp.: 801 °F
• expl. lim.: 2.2-11.5 %, 38 °F
• impurities: ≤0.0009 meq/g Titr. acid; <0.01% water
• evapn. residue: <0.0003%
• refractive index: n20/D 1.3720 (lit.)
• bp: 76.5-77.5 °C (lit.)
• mp: −84 °C (lit.)
• solubility: alcohol: soluble(lit.); water: soluble(lit.)
• density: 0.902 g/mL at 25 °C (lit.)
• λ: H₂O reference
• UV absorption: λ: 254 nm A_max: 1.00; λ: 263 nm A_max: 0.05; λ: 275-400 nm A_max: 0.01
• format: neat
• SMILES string: CCOC(C)=O
• InChI: 1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
• InChI key: XEKOWRVHYACXOJ-UHFFFAOYSA-N

Description

General description

Ethyl acetate (EA), a carboxylate ester, is bio-friendly organic solvent with a wide range of industrial applications. Its synthesis by reactive distillation and by acceptorless dehydrogenative dimerization of ethanol has been explored. Its utility as a less toxic alternative to diethyl ether in the formalin-ether (F-E) sedimentation procedure for intestinal parasites has been investigated. Its ability as an acyl acceptor in the immobilized lipase-mediated preparation of biodiesel from crude vegetable oils has been examined. The complete degradation of ethyl acetate to CO₂ using manganese octahedral molecular sieve (OMS-2) has been investigated. Low water content, minimal residue and clean UV spectra are the special characteristics of this biotech grade solvent. It can be utilized for biotechnological processes like protein sequencing, peptide and oligonucleotide synthesis.

Application

Ethyl acetate may be used in the following processes:

• Preparation of thin films of TiO₂ (titanium dioxide) on glass.
• As an extraction medium in the multi-residue analysis of pesticide residues in fruit and vegetables.
• Acetylation of primary amines to form amides in the presence of dimethyltin(IV) acetic acid distannoxane.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H336
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• Supplementary Hazards: EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 24.8 °F - closed cup
• Flash Point(C): -4 °C - closed cup