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33457

Sigma-Aldrich

2-Methoxyethanol

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.5% (GC)

Synonym(s):

Ethylene glycol monomethyl ether, Methyl glycol

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About This Item

Linear Formula:
CH3OCH2CH2OH
CAS Number:
109-86-4
Molecular Weight:
76.09
Beilstein:
1731074
EC Number:
203-713-7
MDL number:
MFCD00002867
UNSPSC Code:
12352112
PubChem Substance ID:
329754554

grade

ACS reagent
puriss. p.a.

Agency

reag. Ph. Eur.

vapor density

2.62 (vs air)

vapor pressure

6.17 mmHg ( 20 °C)

Assay

≥99.5% (GC)

form

liquid

autoignition temp.

548 °F

expl. lim.

24.5 %

impurities

≤0.0003% peroxides (as H2O2)
≤0.001% acetaldehyde
≤0.001% formaldehyde
≤0.002% non-volatile matter
≤0.002 meq/g free acid (as CH3COOH)
≤0.1% water (Karl Fischer)

refractive index

n20/D 1.4010-1.4030
n20/D 1.402 (lit.)

bp

124-125 °C (lit.)

mp

−85 °C (lit.)

density

0.966-0.968 g/mL at 20 °C
0.965 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg
B: ≤0.02 mg/kg
Ba: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Fe: ≤0.4 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sn: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

SMILES string

COCCO

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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General description

2-Methoxyethanol is widely used solvent in various electrochemical studies and industrial units. It exhibits “quasi-aprotic properties. Its solvent characteristics are a mixture of the protic and aprotic solvents. Dissolution of alkali metal salts in 2-methoxyethanol have been studied and their conductance, viscosity and laser-Raman spectra have been evaluated.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B - STOT RE 2 - STOT SE 1

Target Organs

Immune system, thymus

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Conductometric, viscometric, and spectroscopic investigations on the solvation phenomena of alkali-metal ions and ion pairs in 2-methoxyethanol.
Das B and Hazra DK.
The Journal of Physical Chemistry, 99(1), 269-273 (1995)
Anna Maria Piras et al.
International journal of pharmaceutics, 357(1-2), 260-271 (2008-03-04)
The preparation of novel biocompatible polymeric nanoconstructs suitable to load sensitive bioactive protein agents is reported. Nanoparticles were prepared as based on hybrid polymeric matrices consisting of synthetic bioerodible alternating copolymers of maleic anhydride and n-butylvinylether hemiesterified with 2-methoxyethanol and
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order
Huiping Yang et al.
Cryobiology, 61(2), 211-219 (2010-07-27)
Medaka Oryzias latipes is a well-recognized biomedical fish model because of advantageous features such as small body size, transparency of embryos, and established techniques for gene knockout and modification. The goal of this study was to evaluate two critical factors
H-Y Chang et al.
Occupational and environmental medicine, 61(8), 697-702 (2004-07-20)
To evaluate the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol (2-ME); and to examine the association of 2-methoxyacetic acid (MAA) in urine and plasma collected simultaneously from low 2-ME exposure and high 2-ME exposure workers in a semiconductor
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