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C2177000

Cinchocaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibucaine hydrochloride, 2-Butoxy-N-(2-diethylaminoethyl)-4-quinolinecarboxamide hydrochloride, Cinchocaine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H29N3O2 · HCl
CAS Number:
Molecular Weight:
379.92
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

cinchocaine

manufacturer/tradename

EDQM

mp

99-101 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1

InChI

1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H

InChI key

IVHBBMHQKZBJEU-UHFFFAOYSA-N

Gene Information

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General description

Cinchocaine hydrochloride is a drug commonly used in ophthalmic ointments to produce conjunctival anaesthesia or in dilute penetrable solutions to produce spinal or surface anesthesia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Potent, long-acting local anesthetic

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry.
Abdel-Ghani NT, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(5), 419-424 (2005)
High-performance liquid chromatographic determination of chlorpromazine and thioridazine hydrochlorides in pharmaceutical formulations.
Mehta A C.
Analyst, 106(1267), 1119-1122 (1981)

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