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Oryzalin

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H18N4O6S
CAS Number:
19044-88-3
Molecular Weight:
346.36
Beilstein:
2177305
EC Number:
242-777-0
MDL number:
MFCD00078725
UNSPSC Code:
41116107
PubChem Substance ID:
329755324
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CCCN(CCC)c1c(cc(cc1[N+]([O-])=O)S(N)(=O)=O)[N+]([O-])=O

InChI

1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)

InChI key

UNAHYJYOSSSJHH-UHFFFAOYSA-N

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General description

Oryzalin is a dinitroaniline herbicide, which can have the tendency to inhibit spindle formation and thereby lead to choromosome doubling in vitro in the diploid hybrid of Rosa rugosa. It can also serve as a potent antiparasitic therapeutic candidate, in the treatment of leishmaniasis disease.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Warning

Hazard Statements

H317,H351,H373,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Skin Sens. 1 - STOT RE 2

Target Organs

Blood,Kidney

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8114
BCCG0802
BCCB2195
BCBZ8664
SZBE118XV

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Chromosome doubling in a Rosa rugosa Thunb. hybrid by exposure of in vitro nodes to oryzalin: the effects of node length, oryzalin concentration and exposure time
Allum.F.J, et al.
Plant Cell Reports, 26(11), 1977-1984 (2007)
Andrew Muroyama et al.
Current biology : CB, 30(22), 4467-4475 (2020-09-19)
Multicellular development depends on generating and precisely positioning distinct cell types within tissues. During leaf development, pores in the epidermis called stomata are spaced at least one cell apart for optimal gas exchange. This pattern is primarily driven by iterative
Rapid and reversible high-affinity binding of the dinitroaniline herbicide oryzalin to tubulin from Zea mays L
Hugdahl.DJ and Morejohn.CL
Plant Physiology, 102(3), 725-740 (1993)
Lili Zhang et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(2), 279-288 (2011-10-25)
It is still unclear how light and gibberellins are integrated to regulate petal size. Here, we report that light improves both the length and the width of the ray floret petals in G. hybrid, but GA(3) promotes only the petal
Rui M Lopes et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(2), 281-290 (2012-07-10)
Oryzalin (ORZ) is a dinitroaniline that has attracted increasing interest for the treatment of leishmaniasis. The possible use of ORZ as an antiparasitic agent is limited by low water solubility associated with an in vivo rapid clearance. The aim of
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