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Key Documents

MAB443

Sigma-Aldrich

Anti-Estrogen Receptor Antibody, clone AER304

ascites fluid, clone AER304, Chemicon®

Synonym(s):

ER

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

AER304, monoclonal

species reactivity

bovine, human, chicken, mouse

manufacturer/tradename

Chemicon®

technique(s)

electrophoretic mobility shift assay: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000125.2

UniProt accession no.

P03372

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ESR1(2099)

Specificity

Estrogen receptor 67kD hormone binding subunit. Epitope localized between aa 120-170.

Immunogen

Bovine estrogen receptor.
Epitope: a.a. 120-170

Application

Anti-Estrogen Receptor Antibody, clone AER304 is a Mouse Monoclonal Antibody for detection of Estrogen Receptor also known as ER & has been validated in EMSA, IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Western blot (human)

Immunoprecipitation (human)

Immunohistochemistry (mouse)

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: 04-227

Physical form

Liquid

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shyam Nathan et al.
Breast cancer research and treatment, 166(3), 681-693 (2017-08-16)
We previously identified small molecules that fit into a BRCA1-binding pocket within estrogen receptor-alpha (ERα), mimic the ability of BRCA1 to inhibit ERα activity ("BRCA1-mimetics"), and overcome antiestrogen resistance. One such compound, the hydrochloride salt of NSC35446 ("NSC35446.HCl"), also inhibited

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