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MAB4023

Sigma-Aldrich

Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2

clone RTJ2, Chemicon®, from mouse

Synonym(s):

HER-3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

RTJ2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_001005915.1
NM_001982.2

UniProt accession no.

P21860

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ERBB3(2065)

Specificity

Reactive with human c-erB-3. In normal tissues, c-erB-3 is found in non-dividing differentiated epithelial cells, neurons, and hepatocytes. In abnormal tissues, c-erB-3 is found in 80% of GI tract tumors and 20% of breast cancers.

Immunogen

Epitope: cytoplasmic domain
Synthetic peptide corresponding to a site on the cytoplasmic domain of the human c-erbB-3 oncoprotein

Application

Detect c-erbB-3 using this Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2 validated for use in ELISA, IH, IP & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Liquid in PBS, containing azide as a preservative.

Storage and Stability

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R Naidu et al.
British journal of cancer, 78(10), 1385-1390 (1998-11-21)
Expression of c-erbB3 protein was investigated in 104 primary breast carcinomas comprising nine comedo ductal carcinoma in situ (DCIS), 91 invasive ductal carcinomas and four invasive lobular carcinomas using two monoclonal antibodies, RTJ1 and RTJ2. Of the 91 invasive ductal

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