Chondroitin sulfate proteoglycan (CSPG), protein core epitope
Immunogen
Epitope: Core Protein Epitope
Application
Immunohistochemistry: 1:2,000 on 4% paraformaldehyde fixed frozen tissue.
Immunocytochemistry: 1:500 on primary cultures of neurons.
Immunoblot: 1:5,000 recognizes a band at 680 kDa.
Immunoprecipitation.
Optimal working dilutions must be determined by the end user.
This Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315 is validated for use in IP, WB, IC, IH for the detection of Chondroitin Sulfate Proteoglycan.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(20), 5405-5413 (2007-05-18)
An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far
Restorative neurology and neuroscience, 35(4), 395-411 (2017-06-10)
Utilizing genetic overexpression of trophic molecules in cell populations has been a promising strategy to develop cell replacement therapies for spinal cord injury (SCI). Over-expressing the chemokine, stromal derived factor-1 (SDF-1α), which has chemotactic effects on many cells of the
Cerebral cortex (New York, N.Y. : 1991), 26(3), 1336-1348 (2016-01-09)
Corticothalamic projection systems arise from 2 main cortical layers. Layer V neurons project exclusively to higher-order thalamic nuclei, while layer VIa fibers project to both first-order and higher-order thalamic nuclei. During early postnatal development, layer VIa and VIb fibers accumulate
Hydrogels are engineered with biochemical and biophysical signals to recreate aspects of the native microenvironment and to control cellular functions such as differentiation and matrix deposition. This deposited matrix accumulates within the pericellular space and likely affects the interactions between
Frontiers in integrative neuroscience, 12, 3-3 (2018-02-20)
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain development. Emerging evidence indicates that PNNs promote the maturation of PV cells
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