Cathepsin Z, also known as Cathepsin P, Cathepsin X, and encoded by the gene name CTSZ, is a member of the the peptidase C1 family. Cathepsin Z is a lysosomal cysteine proteinase that exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. Cathepsin Z is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined.
Immunogen
Epitope: Near C-terminus
KLH-conjugated linear peptide corresponding to human Cathepsin Z near the C-terminus.
Application
Research Category Apoptosis & Cancer
Research Sub Category Apoptosis - Additional
This Anti-Cathepsin Z antibody is validated for use in Western Blotting for the detection of Cathepsin Z.
Quality
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Cathepsin Z in 10 µg of human liver tissue lysate.
Target description
~33 kDa observed. (Pungecar, J., et al. (2000). PMID: 10653163)
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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