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640001P

Avanti

Ceramide Delivery System

Avanti Research - A Croda Brand

Synonym(s):

Ceramide Delivery System, Kit for C6 Ceramide Delivery

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.28

Assay

>99%

form

powder

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

Ceramide forms stable, fluid bilayers with cholesteryl phosphocholine, and this formulation has been shown to be more potent than solvent-delivered (DMSO) formulations of C6 Ceramide in inhibiting proliferation, inducing apoptosis, and disturbing calcium homeostasis. It is thought that DMSO formulations of C6 Cer are likely to precipitate into the cell culture medium, where the bioavailability of “crystalline” ceramide is limited. However, the formation of fluid bilayers, which are enriched in C6 Cer, prevent crystallization and allow for the transfer of monomeric ceramide to cell membranes with enhanced bioavailability.

Packaging

The kit contains 10 mg of C6 Ceramide and 13.8 mg of Cholesteryl Phosphocholine, individually packaged and ready for use.

Other Notes

Note: This delivery system works primarily with short-chain ceramides. Delivery of long-chain ceramides, e.g., C16 Cer, was generally low or absent during similar incubation times.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Kit Components Also Available Separately

Product No.
Description
SDS

  • 700123PCholPC, Avanti Research - A Croda Brand 700123P, powderSDS

  • 860506PC6 Ceramide (d18:1/6:0), Avanti Research - A Croda BrandSDS

Storage Class Code

10 - Combustible liquids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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