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96895

Sigma-Aldrich

Z-Lys-ONp hydrochloride

≥98.0% (AT)

Synonym(s):

Nα-Z-L-lysine 4-nitrophenyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H23N3O6 · HCl
CAS Number:
2179-15-9
Molecular Weight:
437.87
Beilstein:
7191805
EC Number:
218-546-5
MDL number:
MFCD00039055
UNSPSC Code:
12352200
PubChem Substance ID:
57653793
NACRES:
NA.22
Pricing and availability is not currently available.

Assay

≥98.0% (AT)

form

powder

optical activity

[α]20/D −24±1°, c = 1% in DMF

mp

146-152 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

Cl.NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C20H23N3O6.ClH/c21-13-5-4-8-18(22-20(25)28-14-15-6-2-1-3-7-15)19(24)29-17-11-9-16(10-12-17)23(26)27;/h1-3,6-7,9-12,18H,4-5,8,13-14,21H2,(H,22,25);1H/t18-;/m0./s1

InChI key

JFZLPXVXTZKFDV-FERBBOLQSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBD9626V
1370163
1325041
1259387
1068283

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R J Szawelski et al.
The Biochemical journal, 199(3), 681-692 (1981-12-01)
1. The hydrolyses of the p-nitrophenyl esters of N-benzyloxycarbonylglycine, alpha-N-benzyloxycarbonyl-L-lysine and N-methoxycarbonyl-L-phenylalanylglycine catalysed by papain (EC 3.4.22.2) have been studied in solvents having a variable composition of 2H2O and H2O. 2. kcat., which represents deacylation in the papain-catalysed hydrolysis of
W S Ferguson et al.
The Journal of experimental medicine, 167(2), 528-540 (1988-02-01)
Target cell lysis by most murine cytotoxic T lymphocytes appears to be mediated by a complement (C9)-like protein called perforin, contained in high-density cytoplasmic granules. These granules also contain high levels of serine esterase activity, which may also play a
P D Compton et al.
The Journal of biological chemistry, 261(3), 1248-1252 (1986-01-25)
The effect of aqueous methanol cryosolvents on the catalytic and structural properties of bovine trypsin has been investigated. The low freezing points and low viscosities of methanol-based cryosolvents are desirable for a variety of cryoenzymological experiments. Increasing concentrations of methanol
J P Malthouse et al.
The Biochemical journal, 215(3), 555-563 (1983-12-01)
A detailed study of the kinetics of the trypsin (EC 3.4.21.4)-catalysed hydrolysis of N-alpha-benzyloxycarbonyl-L-lysine p-nitrophenyl ester in cryosolvents at 0 degrees C and below was undertaken. The pH-dependences of kcat, Km, k+2, k+3 and Ks were determined under cryoenzymological conditions
P Ascenzi et al.
Biochimica et biophysica acta, 789(1), 99-103 (1984-08-28)
The values of pre-steady-state and steady-state parameters for the beta-trypsin catalyzed hydrolysis of Z-Arg-ONp and Z-Lys-ONp are superimposable between pH 2.4 and 8. At variance, the kinetic parameters for the beta-kallikrein-B catalyzed hydrolysis of Z-Arg-ONp are more favourable than those
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