Skip to Content
Merck
All Photos(1)

Documents

930016

Sigma-Aldrich

TissueFab® bioink 

Facile Curable GelHA, Ionic

Synonym(s):

3D bioprinting, Bioink, Facile Curable, Gelatin, Hyaluronic Acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

100

sterility

0.2 μm filtered

form

viscous liquid ((or gel))

impurities

<5 CFU/g Bioburden (Total Aerobic)
<5 CFU/g Bioburden (fungal)
<50 EU/mL Endotoxin

color

colorless to pale yellow

pH

6.5-7.5

viscosity

5-35 cP(37 °C)

application(s)

3D bioprinting

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

General description

Facile curable bioinks are ready-to-print bioinks formulated to crosslink without the necessity of light irradiation which can be detrimental to cell health. The bioink has a Gelatin base which as a natural protein offers excellent cytocompatibility and cell-binding motifs in order to mimic the native extracellular (ECM) microenvironment. The bioink can be crosslinked in a dilute solution of multivalent cations including TissueFab® - crosslinking solution (Cat#919926). TissueFab® - Facile curable HA bioink also contains hyaluronic acid (HA), a natural polysaccharide found ubiquitously throughout the body and cellular ECM. Cell can recognize HA through cell surface receptors CD44 and RHAMM and also degrade it through secretion of hyaluronidase.

Low bioburden: Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/microbiological-testing/pyrogen-testing/what-is-endotoxin

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service