721778

N,N-Dimethylformamide dimethyl sulfate adduct

95%

• Synonym(s): DMF-Dimethyl sulfate, Methoxymethylene-N,N-dimethyliminium methyl sulfate
• Empirical Formula (Hill Notation): C₅H₁₃NO₅S
• CAS Number: 89712-45-8
• Molecular Weight: 199.23
• MDL number: MFCD16621484
• UNSPSC Code: 12352108
• PubChem Substance ID: 329763872
• NACRES: NA.22

Properties

• Assay: 95%
• form: liquid
• refractive index: n20/D 1.459
• density: 1.349 g/mL at 25 °C
• SMILES string: CN(C)C=O.COS(=O)(=O)OC
• InChI: 1S/C3H7NO.C2H6O4S/c1-4(2)3-5;1-5-7(3,4)6-2/h3H,1-2H3;1-2H3
• InChI key: UJKUJXVZLUTEAZ-UHFFFAOYSA-N

Description

Application

DMF-Dimethyl sulfate adduct can be used as a reagent to synthesize:

• 2-azetidinones by a reaction between Schiff bases and substituted acetic acids.
• Dimethylamino methylene derivatives, which can be employed in the preparation of fluoroquinolines and 3-amino-4-cyano pyrazole.
• Cis β-sultams by [2 + 2] annulation of aldimines with sulfonic acids.

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331,H315,H318,H334,H335,H350
• Precautionary Statements: P202 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 190.0 °F - closed cup
• Flash Point(C): 87.8 °C - closed cup