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About This Item
Linear Formula:
C2H5ONO
CAS Number:
Molecular Weight:
75.07
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form:
liquid
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form
liquid
concentration
10-20 wt. % in ethanol
refractive index
n20/D 1.36
density
0.792 g/mL at 25 °C
functional group
O-nitroso
nitroso
storage temp.
2-8°C
SMILES string
CCON=O
InChI
1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
InChI key
QQZWEECEMNQSTG-UHFFFAOYSA-N
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General description
The reactions of ethyl nitrite solution with human haemoglobin and sperm whale myoglobin were studied[1].
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
59.0 °F - closed cup
Flash Point(C)
15 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M P Doyle et al.
The Journal of biological chemistry, 256(23), 12399-12404 (1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to their oxidized counterparts with concurrent production of one equivalent
Kazufumi Shimazutsu et al.
Clinical and translational science, 2(6), 405-412 (2010-05-07)
A method to maintain organ blood flow during laparoscopic surgery has not been developed. Here we determined if ethyl nitrite, an S-nitrosylating agent that would maintain nitric oxide bioactivity (the major regulator of tissue perfusion), might be an effective intervention
Richard L Auten et al.
American journal of respiratory and critical care medicine, 176(3), 291-299 (2007-05-05)
Inhaled nitric oxide (NO) has been used to prevent bronchopulmonary dysplasia, but with variable results. Ethyl nitrite (ENO) forms S-nitrosothiols more readily than does NO, and resists higher-order nitrogen oxide formation. Because S-nitrosylation is a key pathway mediating many NO
Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
Steven H Abman et al.
Lancet (London, England), 360(9350), 2076-2077 (2002-12-31)
Basil M Yurcisin et al.
Annals of surgery, 257(5), 971-977 (2013-01-31)
To determine if reduction in nitric oxide bioactivity contributes to the physiological instability that occurs after brain death and, if so, to also determine in this setting whether administration of a renitrosylating agent could improve systemic physiological status. Organ function
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