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Sigma-Aldrich

N-Boc- 2,2′-(ethylenedioxy)diethylamine

≥95.0% (NT), for peptide synthesis

Synonym(s):

N-Boc-3,6-dioxa-1,8-octanediamine, tert-Butyl 2-[2-(2-aminoethoxy)ethoxy]ethylcarbamate

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About This Item

Empirical Formula (Hill Notation):
C11H24N2O4
CAS Number:
Molecular Weight:
248.32
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

product name

N-Boc- 2,2′-(ethylenedioxy)diethylamine, ≥95.0% (NT)

Quality Level

Assay

≥95.0% (NT)

form

liquid

reaction suitability

reagent type: cross-linking reagent

density

1.046 g/mL at 20 °C

functional group

Boc
amine

SMILES string

NCCOCCOCCNC(OC(C)(C)C)=O

InChI

1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)

InChI key

OCUICOFGFQENAS-UHFFFAOYSA-N

Application

Linker reagent for the prep. of a broad variety of linked tags, monomers for polymerisation, ionophores etc., e.g. biotinylation reagents.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Braun, M., et al.
European Journal of Organic Chemistry, 7, 1173 - 1182 (2000)
Michelle Trester-Zedlitz et al.
Journal of the American Chemical Society, 125(9), 2416-2425 (2003-02-27)
A method is described for the elucidation of protein-protein interactions using novel cross-linking reagents and mass spectrometry. The method incorporates (1) a modular solid-phase synthetic strategy for generating the cross-linking reagents, (2) enrichment and digestion of cross-linked proteins using microconcentrators
Spinke, J., et al.
The Journal of Physical Chemistry, 99(9), 7012-7019 (1993)
Sigal, G. B., et al.
Journal of the American Chemical Society, 118, 3789-3800 (1996)

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