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435449

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

average Mn ~2,900

Synonym(s):

Pluronic® L-64, PEG-PPG-PEG

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About This Item

CAS Number:
9003-11-6
MDL number:
MFCD00082049
UNSPSC Code:
12352104
PubChem Substance ID:
24867234
NACRES:
NA.23
Pricing and availability is not currently available.

vapor density

>1 (vs air)

vapor pressure

<0.3 mmHg ( 20 °C)

form

viscous liquid

mol wt

average Mn ~2,900

composition

PEG, 40 wt. %

refractive index

n20/D 1.46

surface tension

43 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

850 cP(25 °C, Brookfield)(lit.)

transition temp

cloud point 58 °C (1 wt. % aqueous solution)

density

1.05 g/mL at 25 °C

HLB

12.0 - 18.0

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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Related Categories

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Physical form

Terminal primary dihydroxy-functional oligomer.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW3532
MKCT8242
MKCT0365
MKCS3385
MKCR2995

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Jianan Shen et al.
Biomaterials, 34(5), 1581-1590 (2012-11-14)
The metastasis of breast cancer is the leading cause of cancer death in women, and the lung is a common location of a secondary tumor that has metastasized from the primary source tumor. In this work, an attempt to simultaneously
Irshad A Wani et al.
Colloids and surfaces. B, Biointerfaces, 101, 243-250 (2012-09-27)
Silver nanoparticles have been synthesized in the inverse microemulsions formed using three different surfactants viz., cetyl-trimethyl ammonium bromide (CTAB), Tergitol and Triton X-100. We have done a systematic study of the effect of the surfactants on the particle size and
Wendell J Lu et al.
Lipids, 47(6), 571-580 (2012-02-03)
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are incretins produced in the intestine that play a central role in glucose metabolism and insulin secretion. Circulating concentrations of GLP-1 and GIP are low and can be difficult to assay in
Yanbin Guan et al.
Archives of pharmacal research, 34(10), 1719-1728 (2011-11-15)
The aim of the present study was to evaluate the effect of pluronic P123 (P123) and pluronic F127 (F127) on intestinal P-glycoprotein (P-gp) and cytochrome P450 3A using the specific substrates rhodamine-123 (R-123) and midazolam, respectively. Caco-2 cells and everted
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
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Mesoporous materials self-assemble from sol-gel precursors and amphiphiles, forming versatile structures for various applications.

Mesoporous Materials Synthesis

Mesoporous materials self-assemble from sol-gel precursors and amphiphiles, forming versatile structures for various applications.

Mesoporous Materials Synthesis

Mesoporous materials self-assemble from sol-gel precursors and amphiphiles, forming versatile structures for various applications.

Questions

1–6 of 6 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the hydrophile-lipophile balance (HLB) of Product 435449, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)?

    1 answer

    1. The hydrophile-lipophile balance (HLB) is between 12.0-18.0.

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  4. What is the softening point of Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)?

    1 answer

    1. The softening point is 16°C.

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  5. What is Product 435449, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), soluble in?

    1 answer

    1. This product is soluble in o-xylene

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  6. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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