Skip to Content
Merck
All Photos(1)

Key Documents

SRP4039

Sigma-Aldrich

Fgf-2 from rat

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Synonym(s):

FGB-b, FGF-2, Fibroblast Growth Factor-basic, HBGF-2, Prostatropin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

rat

recombinant

expressed in E. coli

Assay

≥97% (HPLC)
≥97% (SDS-PAGE)

form

lyophilized

potency

<0.2 ng/mL

mol wt

~16.3 kDa

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

P13109

UniProt accession no.

P13109

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Fgf2(54250)

General description

Fibroblast growth factor-2 (FGF-2) is a basic heparin binding growth factor and a profibrotic factor. The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Biochem/physiol Actions

Fibroblast growth factor-2 (FGF-2) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.

Physical form

Lyophilized from 1 mg/ml solution after extensive dialysis against 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 0.1–1 mg/mL.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Liu Y
Journal of the American Heart Association, 4(7), e001598-e001598 (2015)
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Hu MC
Molecular and Cellular Biology, 18(10), 6063-6074 (1998)
Larisa Antonova et al.
Pharmaceuticals (Basel, Switzerland), 14(4) (2021-04-04)
Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an overdose
Senthil S Saravanamuthu et al.
Developmental biology, 332(1), 166-176 (2009-06-02)
Previous studies of the developing lens have shown that Notch signaling regulates differentiation of lens fiber cells by maintaining a proliferating precursor pool in the anterior epithelium. However, whether Notch signaling is further required after the onset of fiber cell
Shun Yamamuro et al.
International journal of oncology, 47(1), 91-96 (2015-05-09)
Glioma stem-like cells (GSCs) could have potential for tumorigenesis, treatment resistance, and tumor recurrence (GSC hypothesis). However, the mechanisms underlying such potential has remained elusive and few ultrastructural features of the cells have been reported in detail. We therefore undertook
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service