SAB3500598

Anti-ZIP8 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-BIGM103, Anti-PP3105, Anti-SLC39A8, Anti-Slc39A8, Anti-Solute carrier family 39 member A8
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI accession no.: NP_071437
• UniProt accession no.: Q9C0K1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SLC39A8(64116)

Description

General description

Solute carrier family 39 member 8 (SLC39A8), also known as zinc- and iron-related protein 8 (ZIP8), is a plasma membrane transporter protein. It is part of the solute carrier gene superfamily. The gene encoding SLC39A8 is localized on human chromosome 4q24.

Immunogen

ZIP8 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human ZIP8.

Application

Anti-ZIP8 antibody produced in rabbit has been used in immunocytochemistry.

Biochem/physiol Actions

Solute carrier family 39 member 8 (SLC39A8) co-transports divalent metal cations like cadmium, zinc, manganese and iron. It has a crucial role in the cellular uptake of cadmium. The protein is a target of nuclear-factor κB (NF-κB) and has a role in pro-inflammatory responses.

Features and Benefits

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Linkage

The action of this antibody can be blocked using blocking peptide SBP3500598.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable