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H7752

Sigma-Aldrich

Serotonin creatinine sulfate monohydrate

≥99% (TLC), powder, neurotransmitter

Synonym(s):

3-[2-Aminoethyl]-5-hydroxyindole creatinine sulfate complex, 5-HT, 5-Hydroxytryptamine creatinine sulfate complex

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About This Item

Empirical Formula (Hill Notation):
C14H19N5O2 · H2O4S · H2O
CAS Number:
61-47-2
Molecular Weight:
405.43
MDL number:
MFCD00149653
UNSPSC Code:
51111800
PubChem Substance ID:
24895804
NACRES:
NA.77

product name

Serotonin creatinine sulfate monohydrate, powder

form

powder

Quality Level

100

color

white to off-white

solubility

0.1 M HCl: soluble (Solutions should be freshly prepared.)
95% ethanol: very slightly soluble (Solutions should be freshly prepared.)
absolute ethanol: insoluble

storage temp.

2-8°C

SMILES string

O.OS(O)(=O)=O.CN1CC(=O)NC1=N.NCCc2c[nH]c3ccc(O)cc23

InChI

1S/C10H12N2O.C4H7N3O.H2O4S.H2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;1-7-2-3(8)6-4(7)5;1-5(2,3)4;/h1-2,5-6,12-13H,3-4,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4);1H2

InChI key

BKCXVJIGPVULPX-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359)

Application

Serotonin creatinine sulfate monohydrate has been used:
  • to study its effect on the feeding motions in Caenorhabditis elegans
  • to study the chronotropic responses of serotonin (5-HT) in the zebrafish heart
  • to study the effect of serotonin on isthmus peristalsis

Biochem/physiol Actions

Serotonin creatinine sulfate stimulates neuronal production of catecholamine.
Neurotransmitter.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Methods for measuring pharyngeal behaviors
WormBook: The Online Review of C. elegans Biology (2005)
Adolfo E Talpalar et al.
Nature, 500(7460), 85-88 (2013-07-03)
All forms of locomotion are repetitive motor activities that require coordinated bilateral activation of muscles. The executive elements of locomotor control are networks of spinal neurons that determine gait pattern through the sequential activation of motor-neuron pools on either side
Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans
Song B and Avery L
The Journal of Neuroscience, 32(6), 1920-1931 (2012)
Effect of serotonin on brown adipose tissue and on its sympathetic neurons
Steiner G and Evans S
The American Journal of Physiology, 231(1), 34-39 (1976)
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