D7911

Decylubiquinone

≥97% (HPLC)

• Synonym(s): 2,3-Dimethoxy-5-methyl-­6-decyl-1,4-benzoquinone
• Empirical Formula (Hill Notation): C₁₉H₃₀O₄
• CAS Number: 55486-00-5
• Molecular Weight: 322.44
• MDL number: MFCD00083306
• UNSPSC Code: 12162212
• PubChem Substance ID: 24894169
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥97% (HPLC)
• form: liquid
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCC1=C(C)C(=O)C(OC)=C(OC)C1=O
• InChI: 1S/C19H30O4/c1-5-6-7-8-9-10-11-12-13-15-14(2)16(20)18(22-3)19(23-4)17(15)21/h5-13H2,1-4H3
• InChI key: VMEGFMNVSYVVOM-UHFFFAOYSA-N

Description

General description

Mitochondrial permeability transition pore (MPTP) inhibitor.

Ubiquinone analog.

Application

• Lysosomal Ca(2+) as a mediator of palmitate-induced lipotoxicity.: This study explores the role of decylubiquinone in modulating lysosomal Ca(2+) levels, providing insights into mechanisms of lipotoxicity and potential therapeutic applications in metabolic diseases (Oh et al., 2023).


• Quinone binding site in a type VI sulfide:quinone oxidoreductase.: This paper investigates the binding dynamics of decylubiquinone in sulfide:quinone oxidoreductase, shedding light on its role in microbial respiration and potential biotechnological applications (Miklovics et al., 2022).


• Protective role of Decylubiquinone against secondary melanoma at lung in B16F10 induced mice.: The study demonstrates the anti-metastatic properties of decylubiquinone in a melanoma mouse model, highlighting its potential as a therapeutic agent in cancer treatment (Chatterjee et al., 2023).


• Decylubiquinone Inhibits Colorectal Cancer Growth Through Upregulating Sirtuin2.: This research identifies decylubiquinone as an inhibitor of colorectal cancer growth by modulating Sirtuin2 expression, suggesting its application in cancer therapeutics (Li et al., 2021).

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves