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Key Documents

59920C

SAFC

EX-CELL® Antifoam

gamma irradiated

Pharma Manufacturing

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

Quality Level

sterility

γ-irradiated

form

liquid

technique(s)

NMR: suitable
cell culture | mammalian: suitable
protein quantification: suitable

suitability

suitable for manufacturing use

shipped in

ambient

Application

EX-CELL® ANTIFOAM is a USP Grade non-ionic emulsion (simethicone) designed for use in the pharmaceutical and veterinary biological industries to aid in the control of foaming typically associated with the use of culture medium in bioreactors.
Through formulation optimization, utilization of a quantitative assay and an understanding of the nonspecific binding of simethicone, SAFC is able to report the actual simethicone concentration of the gamma irradiated finished material. As a result of this development, SAFC offers an optimized formulation ensuring a consistent product.
This product is of non-animal origin formulated from a 30% Simethicone Emulsion from DOW CORNING Q7-2587

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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High-density mammalian cell cultures in stirred-tank bioreactor without external pH control.
Xu S and Chen H
Journal of Biotechnology, 231, 149-149 (2016)
A practical approach in bioreactor scale-up and process transfer using a combination of constant P/V and vvm as the criterion.
Xu S et al.
Biotechnology Progress, doi: 10-doi: 10 (2017)
Bioreactor productivity and media cost comparison for different intensified cell culture processes.
Xu S et al.
Biotechnology Progress, doi: 10-doi: 10 (2016)
David N Powers et al.
Biotechnology progress, 35(6), e2894-e2894 (2019-08-20)
Real-time monitoring of cell cultures in bioreactors can enable expedited responses necessary to correct potential batch failure perturbations which may normally go undiscovered until the completion of the batch and result in failure. Currently, analytical technologies are dedicated to real-time

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