50200

Gly-Gly

≥99.0% (NT), suitable for ligand binding assays, BioXtra

• Synonym(s): Diglycine, Glycyl-glycine
• Linear Formula: NH₂CH₂CONHCH₂COOH
• CAS Number: 556-50-3
• Molecular Weight: 132.12
• Beilstein: 1765223
• EC Number: 209-127-8
• MDL number: MFCD00008130
• UNSPSC Code: 12161700
• PubChem Substance ID: 329757576
• NACRES: NA.25

Properties

• product name: Gly-Gly, BioXtra, ≥99.0% (NT)
• product line: BioXtra
• Quality Level: 200
• Assay: ≥99.0% (NT)
• form: powder
• technique(s): ligand binding assay: suitable
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤1% loss on drying, 110 °C
• color: white
• useful pH range: 7.5-8.9
• pKa (25 °C): 8.2
• mp: 220-240 °C (dec.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: NCC(=O)NCC(O)=O
• InChI: 1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
• InChI key: YMAWOPBAYDPSLA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves