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BCR266

7H-Dibenzo[c,g]carbazole

BCR®, certified reference material

Synonym(s):

3,4,5,6-Dibenzocarbazole

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About This Item

Empirical Formula (Hill Notation):
C20H13N
CAS Number:
194-59-2
Molecular Weight:
267.32
Beilstein:
213015
MDL number:
MFCD00215941
UNSPSC Code:
41116107
PubChem Substance ID:
329773800
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

[H]n1c2ccc3ccccc3c2c4c1ccc5ccccc45

InChI

1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H

InChI key

STJXCDGCXVZHDU-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR266

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H319,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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O Dorchies et al.
Toxicologic pathology, 29(5), 528-534 (2001-11-07)
The purpose of this work was to investigate the administration of very low but repeated doses of a genotoxic carcinogen and an eventual correlation with cellular DNA synthesis. The compound 7H-dibenzo[c,g]carbazole is a genotoxic carcinogen in the mouse liver and
Zuzana Valovicová et al.
Mutation research, 665(1-2), 51-60 (2009-05-12)
Liver progenitor (oval) cells are a potential target cell population for hepatocarcinogens. Our recent study showed that the liver carcinogens 7H-dibenzo[c,g]carbazole (DBC) and 5,9-dimethyldibenzo[c,g]carbazole (DiMeDBC), but not the sarcomagen N-methyldibenzo[c,g]carbazole (N-MeDBC), induced several cellular events associated with tumor promotion in
Glenn Talaska et al.
Toxicology letters, 162(2-3), 246-249 (2005-11-01)
Studies of the impact of phase 1 enzyme polymorphisms on genetic damage have yielded mixed results. We studied how genetic damage would be altered when specific genes were ablated under low dose conditions. Knockouts (KO) were generated from c57bl6/J mice
G Ericson et al.
Mutation research, 454(1-2), 11-20 (2000-10-18)
The time-course and dose dependent formation of DNA adducts in juvenile northern pike (Esox lucius) following a single exposure to a mixture of benzo[a]pyrene (BaP), benzo[k]fluoranthene (BkF) and 7H-dibenzo[c,g]carbazole (DBC) were investigated by use of the (32)P-postlabelling assay. A complex
T O'Brien et al.
Toxicology in vitro : an international journal published in association with BIBRA, 16(3), 235-243 (2002-05-22)
7H-Dibenzo[c,g]carbazole (DBC) is a model N-heterocyclic aromatic compound (NHA) which is both a hepatotoxin and hepatocarcinogen in rodents. The focus of this investigation was to determine whether human liver cell lines display differential sensitivities to DBC-induced toxicity. Treatment of cell
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