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A3658

Supelco

N8-Acetylspermidine dihydrochloride

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C9H21N3O · 2HCl
CAS Number:
Molecular Weight:
260.20
Beilstein:
3698131
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

technique(s)

mass spectrometry (MS): suitable

format

neat

storage temp.

2-8°C

SMILES string

Cl.Cl.CC(=O)NCCCCNCCCN

InChI

1S/C9H21N3O.2ClH/c1-9(13)12-8-3-2-6-11-7-4-5-10;;/h11H,2-8,10H2,1H3,(H,12,13);2*1H

InChI key

BWGUIRARVGYOIR-UHFFFAOYSA-N

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Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Measurement of spermidine/spermine N1-acetyltransferase activity.
H M Wallace et al.
Methods in molecular biology (Clifton, N.J.), 79, 59-68 (1998-02-17)
B L O'Brien et al.
Digestive diseases and sciences, 40(6), 1269-1274 (1995-06-01)
Urinary N1-acetylspermidine (N1SPD) and N8-acetylspermidine (N8SPD) were measured in 24-hr urine specimens from 42 patients with colon adenocarcinoma and 29 healthy controls to assess their use as markers for colon cancer screening. Serial spot urines in four controls demonstrated significant
A N Kingsnorth et al.
European journal of cancer & clinical oncology, 21(9), 1057-1062 (1985-09-01)
Normal tissues contain only trace amounts of monoacetylated polyamines. N1-Acetylspermidine is present in high concentrations in mouse liver cells damaged by hepatotoxins and is also found in specialised cells of the hamster epididymis. In the present study human breast cancers
Assay of N8-acetylspermidine deacetylase.
J Blankenship
Methods in molecular biology (Clifton, N.J.), 79, 77-80 (1998-02-17)
J Ekström et al.
Acta physiologica Scandinavica, 135(3), 255-261 (1989-03-01)
Polyamines are important for protein synthesis and tissue growth. In rat salivary glands, the activity of ornithine decarboxylase (ODC), the enzyme catalysing the formation of putrescine, and the content of putrescine, spermidine, spermine and N1-acetylspermidine were assayed after parasympathetic or

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