106232
Trifluoroacetic anhydride
ReagentPlus®, ≥99%
Synonym(s):
TFAA
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All Photos(3)
About This Item
Linear Formula:
(CF3CO)2O
CAS Number:
Molecular Weight:
210.03
Beilstein:
746197
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
vapor pressure
6.28 psi ( 20 °C)
Quality Level
100
200
product line
ReagentPlus®
Assay
≥99%
refractive index
n20/D 1.3 (lit.)
bp
39.5-40 °C (lit.)
mp
−65 °C (lit.)
density
1.511 g/mL at 20 °C (lit.)
SMILES string
FC(F)(F)C(=O)OC(=O)C(F)(F)F
InChI
1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
InChI key
QAEDZJGFFMLHHQ-UHFFFAOYSA-N
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Application
For the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for GC analysis. Also used in the oxidation of aldehydes to acids, esters, or amides. Trifluoroacetic anhydride can undergo reaction with deoxyguanosine in pyridine to give the corresponding 6-substituted-2′-deoxyguanosine derivatives. It can also react with urea-hydrogen peroxide complex to generate peroxytrifluoroacetic acid, which can convert aldoximes to nitroalkanes.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Supplementary Hazards
Storage Class Code
8B - Non-combustible corrosive hazardous materials
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Tetrahedron Letters, 27, 3995-3995 (1986)
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