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Key Documents

8.18831

Sigma-Aldrich

Diisobutyl ketone

for synthesis

Synonym(s):

Diisobutyl ketone, Di-iso-butyl ketone, 2,6-Dimethyl-4-heptanone, Isobutyl ketone

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About This Item

Linear Formula:
(CH3)2CHCH2COCH2CH(CH3)2
CAS Number:
Molecular Weight:
142.24
MDL number:
UNSPSC Code:
12352115
EC Index Number:
203-620-1
NACRES:
NA.22

vapor pressure

1.6 hPa ( 20 °C)

Quality Level

form

liquid

autoignition temp.

345 °C

potency

5750 mg/kg LD50, oral (Rat)
16000 mg/kg LD50, skin (Rabbit)

expl. lim.

0.8-6.2 % (v/v)

bp

163-173 °C/1013 hPa

mp

-41 °C

transition temp

flash point 47 °C

solubility

0.5 g/L

density

0.81 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C9H18O/c1-7(2)5-9(10)6-8(3)4/h7-8H,5-6H2,1-4H3

InChI key

PTTPXKJBFFKCEK-UHFFFAOYSA-N

Application


  • Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane extraction.: This research demonstrates the application of diisobutyl ketone in electromembrane extraction techniques, significantly enhancing the selectivity and sensitivity of peptide analysis. This method holds potential for advancing proteomic studies and clinical diagnostics (Balchen M et al., 2012).

  • Direct determination of bromine in plastics by electrothermal vaporization/inductively coupled plasma mass spectrometry using a tungsten boat furnace vaporizer and an exchangeable sample cuvette system.: Highlights the role of diisobutyl ketone in preparing plastic samples for bromine analysis, addressing significant challenges in environmental monitoring and recycling processes (Okamoto Y et al., 2010).

  • Flow injection wetting-film extraction system for flame atomic absorption spectrometric determination of cadmium in environmental waters.: Discusses a novel method involving diisobutyl ketone for the extraction of cadmium from environmental waters, contributing to enhanced detection capabilities in pollution monitoring and water safety (Adam IS et al., 2009).

  • [Thermal desorption gas chromatography for determination of diisobutyl ketone in air of working places].: This study uses diisobutyl ketone in a thermal desorption gas chromatography method to measure workplace air quality, essential for occupational health and safety regulations in industrial environments (Chen W et al., 2008).

  • Synthesis of the O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine oximes of selected carbonyl compounds and their determination by liquid chromatography with ultraviolet detection.: Research on diisobutyl ketone involves its use in synthesizing chemical derivatives for improved UV detection in liquid chromatography, enhancing analytical accuracy in chemical and pharmaceutical analyses (Wiesenthal K et al., 2000).

Analysis Note

Sum of 2,6-Dimethyl-4-heptanone and 2,4-Dimethyl-6-heptanone (GC, area%): ≥ 96.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.807 - 0.811
Identity (IR): passes test

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

120.2 °F - closed cup

Flash Point(C)

49 °C - closed cup


Certificates of Analysis (COA)

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