05-903
Anti-GSK3α/β Antibody, rabbit monoclonal
Upstate®, from rabbit
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About This Item
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GSK3A(2931)
Specificity
GSK3 alpha and beta
Predicted to cross-react with rat based on sequence homology
Immunogen
N-terminal 6His-tagged recombinant full length human GSK3β
Application
Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.
Quality
routinely evaluated by immunoblot on lysates from HEK293 cells
Target description
Mr 46kDa (beta) and 51kDa (alpha)
Physical form
Format: Purified
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(7), 1397-1411 (2011-03-11)
Bipolar disorder (BP) is a debilitating psychiatric disorder, affecting ∼2% of the worldwide population, for which the etiological basis, pathogenesis, and neurocircuitry remain poorly understood. Individuals with BP suffer from recurrent episodes of mania and depression, which are commonly treated
Circulation research, 103(3), 307-314 (2008-06-28)
The inactivation of glycogen synthase kinase-3beta (GSK-3beta) is proposed as the event integrating protective pathways initiated by preconditioning and other interventions. The inactivation of GSK-3 is thought to decrease the probability of opening of the mitochondrial permeability transition pore. The
The neuron-specific isoform of glycogen synthase kinase-3beta is required for axon growth.
Journal of Neurochemistry, 113, 117-130 (2010)
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