Skip to Content
Merck
All Photos(1)

Documents

860546P

Avanti

C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z))

Avanti Research™ - A Croda Brand 860546P, powder

Synonym(s):

D-galactosyl-β-1,1′ N-nervonoyl-D-erythro-sphingosine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C48H91NO8
CAS Number:
17283-91-9
Molecular Weight:
810.24
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860546P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860546P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

InChI

1S/C48H91NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,41-43,45-48,50-51,53-55H,3-16,19-34,36,38-40H2,1-2H3,(H,49,52)/b18-17-,37-35+/t41?,42-,43-,45+,46+,47-,48+/m1/s1

InChI key

WBOZIXHPUPAOIA-KVGFKTOYSA-N

General description

β-Galactosylceramides (GalCers) or cerebrosides are synthesized from the glycosphingolipids by or β-GalCer synthase. They are localized in cytosolic face cell membrane after synthesis from Golgi and endoplasmic reticulum. GalCers are present in the brain and myelin structures.

Application

C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z)) is suitable for use
  • as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
  • as a lipid standard in ozone-induced dissociation mass spectrometry
  • in lipid nanotubes (LNT) preparation in combination with phosphatidylserine

Biochem/physiol Actions

β-Galactosylceramides (GalCers) levels are elevated in Krabbe′s disease due to the galactosylceramidase enzyme deficiency. High levels of nervonic acid-containing ceramide (d18:1/24:1) is associated with aging.

Packaging

5 mL Amber Glass Screw Cap Vial (860546P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus
Vozella V, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(12), 1502-1511 (2017)
Helical organization of blood coagulation factor VIII on lipid nanotubes
Miller J, et al.
Journal of Visualized Experiments, 28(88), e51254-e51254 (2014)
Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics
Han X and Cheng H
Journal of Lipid Research, 46(1), 163-175 (2005)
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals
Von Gerichten J, et al.
Journal of Lipid Research, 58(6), 1247-1258 (2017)
Structural analysis of unsaturated glycosphingolipids using shotgun ozone-induced dissociation mass spectrometry
Barrientos RC, et al.
Journal of the American Society For Mass Spectrometry, 28(11), 2330-2343 (2017)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service