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391956

Sigma-Aldrich

Dimethylamine solution

2.0 M in THF

Synonym(s):

N,N-Dimethylamine

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About This Item

Linear Formula:
(CH3)2NH
CAS Number:
124-40-3
Molecular Weight:
45.08
Beilstein:
605257
MDL number:
MFCD00008288
UNSPSC Code:
12352116
PubChem Substance ID:
24864412
NACRES:
NA.22

form

liquid

Quality Level

200

concentration

1.90-2.20 M (by NaOH, titration)
2.0 M in THF

bp

~60 °C

density

0.85 g/mL at 25 °C

SMILES string

CNC

InChI

1S/C2H7N/c1-3-2/h3H,1-2H3

InChI key

ROSDSFDQCJNGOL-UHFFFAOYSA-N

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Application

Dimethylamine solution (2M in THF) has been used in the synthesis of 2-dimethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (bk-MDDMA) , a β-keto derivative of 3,4-methylenedioxyamphetamine (MDA) by reacting with 2-bromo-3′,4′-methylenedioxypropiophenone. It may also be used to synthesize organic intermediates such as dimethyl-(4-nitro-benzyl)-amine, dimethyl-(4-methyl-benzyl)-amine and 4-dimethylamino-but-2-enoic acid [4-(3,4-dichloro-6-fluoro-phenylamino)-quinazolin-6-yl]-amide.

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Description
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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-32.8 °F - closed cup

Flash Point(C)

-36 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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