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Key Documents

177377

Sigma-Aldrich

Diphenylcyclopropenone

98%

Synonym(s):

DPC

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About This Item

Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

118-122 °C (lit.)

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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General description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Application

Diphenylcyclopropenone was used in topical immunotherapy.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
T Kjeld et al.
Scandinavian journal of medicine & science in sports, 25(3), e253-e257 (2014-08-22)
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive protein, pro-atrial natriuretic peptide, and troponin T.
Yunseok Choi et al.
Annals of dermatology, 25(4), 434-439 (2013-12-29)
There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. We aimed to evaluate the effectiveness and preference of topical immunotherapy with
Leena M Koulu et al.
The Journal of investigative dermatology, 130(11), 2578-2582 (2010-07-09)
Polymorphic light eruption (PLE) is a common skin disorder provoked by exposure to UVR. Its clinical symptoms resemble those of a contact allergic reaction. PLE is generally considered a T-cell-mediated autoimmune reaction toward a yet unidentified antigen formed in UVR-exposed
Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of

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