1369419

Lomustine

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
• Fórmula empírica (notación de Hill): C₉H₁₆ClN₃O₂
• Número CAS: 13010-47-4
• Peso molecular: 233.70
• NACRES: NA.24
• PubChem Substance ID: 329750252
• UNSPSC Code: 41116107
• MDL number: MFCD00012392

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: lomustine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: ClCCN(N=O)C(=O)NC1CCCCC1
• InChI: 1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
• InChI key: GQYIWUVLTXOXAJ-UHFFFAOYSA-N

Descripción

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.

This product is provided as delivered and specified by the issuing Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

Application

Lomustine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Lomustine
• Lomustine Capsules

Biochem/physiol Actions

Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H350
• pcodes: P201 - P280 - P301 + P330 + P331 + P310 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable