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Merck

73035AST

Supelco

Astec® CHIRALDEX G-TA Capillary GC Column

L × I.D. 50 m × 0.25 mm, df 0.12 μm

Sinónimos:

GC column, chiral, gamma-dextran

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About This Item

Código UNSPSC:
41115710
NACRES:
SB.54

Materiales

fused silica

Nivel de calidad

descripción

GC capillary column

envase

pkg of 1 ea

Parámetros

-10-180 °C temperature (isothermal or programmed)

Valor Beta

500

df

0.12 μm

técnicas

gas chromatography (GC): suitable

L × D.I.

50 m × 0.25 mm

grupo activo de la matriz

non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase

aplicaciones

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
life science and biopharma
personal care
pharmaceutical (small molecule)

tipo de columna

capillary chiral

técnica de separación

chiral

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Descripción general

Astec® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.

Aplicación


  • Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation. Application to enzymatic reactions.: This study explores the use of the Astec CHIRALDEX G-TA Capillary GC Column for enantioselective gas chromatographic analysis. The method involves on-line derivatization, enabling the analysis of aqueous samples and applying this technique to enzymatic reactions. This innovative approach highlights the column′s capability in achieving high selectivity and sensitivity for chiral compounds in complex matrices (Mommers et al., 2008).

Resistencia química o física

Temp. Limits:
  • -10 °C to 180 °C isothermal and programmed

Otras notas

We offer a variety of chromatography accessories including analytical syringes

Información legal

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIRALDEX is a trademark of Sigma-Aldrich Co. LLC

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Visite la Librería de documentos

Asymmetric ring opening of meso-epoxides with B-halobis(2-isocaranyl)boranes 2-dIcr2BX
Roy, Chandra D., Brown, Herbert C.
Tetrahedron Asymmetry, 17 (13), 1931-1936 (2006)
Kinetic resolutions concentrate the minor enantiomer and aid measurement of high enantiomeric purity.
Caron, Gaetan; Tseng, George W.M.; Kazlauskas, R.J.
Tetrahedron Asymmetry, 5 (1), 83-92 (1994)
Catalytic asymmetric synthesis of Japonilure and its enantiomer
Xu, Hao, et al.
Tetrahedron Asymmetry, 25 (20-21), 1372-1375 (2014)
Hugo L van Beek et al.
FEBS open bio, 4, 168-174 (2014-03-22)
Enzyme stability is an important parameter in biocatalytic applications, and there is a strong need for efficient methods to generate robust enzymes. We investigated whether stabilizing disulfide bonds can be computationally designed based on a model structure. In our approach
Investigation of a novel diamine based chiral auxiliary in the asymmetric alkylation of ketones
Clarke, Sarah L, et al.
Tetrahedron Asymmetry, 25 (4), 356-361 (2014)

Artículos

Chromatographic enantiomeric separation of amino acids, like proline, is described for chiral GC analysis after derivatization.

Chromatographic enantiomeric separation of amino acids, like proline, is described for chiral GC analysis after derivatization.

Chromatographic enantiomeric separation of amino acids, like proline, is described for chiral GC analysis after derivatization.

Chromatographic enantiomeric separation of amino acids, like proline, is described for chiral GC analysis after derivatization.

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