T3251

(±)-α-Tocoferol

synthetic, ≥96% (HPLC)

• Sinónimos: DL-todo-rac-α-Tocoferol, Vitamina E
• Fórmula empírica (notación de Hill): C₂₉H₅₀O₂
• Número de CAS: 10191-41-0
• Peso molecular: 430.71
• Beilstein: 94012
• Número CE: 233-466-0
• Número MDL: MFCD00006848
• Código UNSPSC: 12352205
• eCl@ss: 34058016
• ID de la sustancia en PubChem: 24900118
• NACRES: NA.77

Propiedades

• origen biológico: synthetic
• Ensayo: ≥96% (HPLC)
• Formulario: liquid
• técnicas: HPLC: suitable
• color: faint brown to brown; yellow to very dark yellow
• solubilidad: H₂O: insoluble; acetone: miscible; chloroform: miscible; ethanol: miscible; vegetable oils: miscible
• densidad: 0.950 g/mL at 20 °C (lit.)
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
• InChI: 1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
• Clave InChI: GVJHHUAWPYXKBD-UHFFFAOYSA-N

Descripción

Aplicación

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Acciones bioquímicas o fisiológicas

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Nota de preparación

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Equipo de protección personal: Eyeshields, Gloves