SML0148

Imidapril hydrochloride

≥98% (HPLC)

• Sinónimos: (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride, Novaloc, TA 6366, Tanapril
• Fórmula empírica (notación de Hill): C₂₀H₂₇N₃O₆ · HCl
• Número de CAS: 89396-94-1
• Peso molecular: 441.91
• Número MDL: MFCD00923828
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329825196
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D -50 to -70° in ethanol (c=0.5)
• color: white to tan
• solubilidad: H₂O: ≥5 mg/mL
• emisor: Trinity Pharma Solutions
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2[C@@H](CN(C)C2=O)C(O)=O
• InChI: 1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
• Clave InChI: LSLQGMMMRMDXHN-GEUPQXMHSA-N

Descripción

Descripción general

Imidapril comprises large acyl moiety and is hydrolyzed by carboxylesterase (CES) 1.

Aplicación

Imidapril hydrochloride may be used to test its effect on pharyngeal and laryngeal muscle to treat impaired swallowing.

Imidapril hydrochloride was used as a standard in bioequivalence test by LC/MS method.

Acciones bioquímicas o fisiológicas

Angiotensin Converting Enzyme (ACE) inhibitor

Imidapril hydrochloride is a long-acting inhibitor of angiotensin converting enzyme used in the treatment of hypertension, congestive heart failure and diabetic nephropathy. It restores decreased airway sensation and bladder sensation in patients with multiple sclerosis.

Imidapril is a potent angiotensin converting enzyme inhibitor and anti-hypertensive.

Características y beneficios

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Trinity Pharma Solutions. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable