SCP0156
Gly-Arg-Ala-Asp-Ser-Pro (GRADSP)
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About This Item
Fórmula empírica (notación de Hill):
C23H39N9O10
Peso molecular:
601.61
UNSPSC Code:
12352209
NACRES:
NA.32
Productos recomendados
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥65%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Gly-Arg-Ala-Asp-Ser-Pro
General description
GRADSP, an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as RGDS (Arg-Gly-Asp-Ser) and GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro).
Gly-Arg-Ala-Asp-Ser-Pro (GRADSP), an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as Arg-Gly-Asp-Ser (RGDS) and Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP).
Application
Gly-Arg-Ala-Asp-Ser-Pro (GRADSP) has been used as a negative control to observe the role of the Arg-Gly-Asp (RGD)-binding integrins in Gal-3-mediated cell adhesion. It has also been used as a control peptide to block the RGD-dependent integrins/integrin signaling.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(9), 3460-3469 (1998-05-09)
The integrin antagonist Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) was applied by local ejection to one of two recording sites in hippocampal slices at various times before and after long-term potentiation (LTP) was induced at both sites with theta burst stimulation. Applications 10 min
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Galectin-3 (Gal-3) is a β-galactoside-binding protein that influences various cell functions, including cell adhesion. We focused on the role of Gal-3 as an extracellular ligand mediating cell-matrix adhesion. We used human adipose tissue-derived stem cells and human umbilical vein endothelial
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