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Merck

SAE0214

Sigma-Aldrich

Leucoagglutinin from P. vulgaris, recombinant

Expressed in P. pastoris, lyophilized powder, suitable for cell culture

Sinónimos:

PHA-L, Phytohemagglutinin-L, Red Kidney Bean Lectin

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.21

Quality Level

form

lyophilized powder

UniProt accession no.

shipped in

wet ice

storage temp.

-10 to -25°C

General description

Lectin from Red Kidney Bean has long been used in a wide variety of applications that require carbohydrate binding including but not limited to T-cell proliferation, leucoagglutination, glycoconjugate capture and more. The native form of lectin from Red Kidney Bean is composed of 2 isolectins (PHA-L and PHA-E) which combine in heterotetromeric combinations that elicit a variety of properties. This recombinant form is strictly the leucoagglutinin (PHA-L) isolectin only, so the erythroagglutinin (PHA-E) isolectin is absent in this product. This allows for more selective performance because there is no chance of PHA-E contamination as seen in native source products.

Biochem/physiol Actions

Kidney bean lectin has a history of being used as a phytohemagglutinin because of its ability to agglutinate blood cells. This isolectin (PHA-L) specficially is the Leucoagglutinin type and can be used for leucoagglutination and as a mitogen. As a lectin, it is known to have some selectivity for binding of β1-6 branched N-glycans.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities
Daniel Bojar
ACS Chemical Biology, 17(11), 2993-3012 (2022)

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