SAB5700367

Anti-Phospho-YAP1-S127 antibody produced in rabbit

• Sinónimos: COB1, YAP, YAP1, YAP2, YAP65, YKI
• UNSPSC Code: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: IF; WB
• species reactivity: mouse, human, rat
• technique(s): immunofluorescence: 1:20-1:100; western blot: 1:500-1:1000

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 36; 48; 49; 50; 52; 53; 54
• species reactivity: mouse, human, rat
• concentration: 0.56 mg/ml
• technique(s): immunofluorescence: 1:20-1:100; western blot: 1:500-1:1000
• UniProt accession no.: P46937
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer127)
• Gene Information: human ... YAP1(10413)

Descripción

General description

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen

A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable