SAB4500814

Anti-Estrogen Receptor-β antibody produced in rabbit

affinity isolated antibody

• Sinónimos: ESR2, ESTRB, Estrogen receptor β, NR3A2
• Número MDL: MFCD01323253
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 59 kDa
• reactividad de especies: human, rat, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q92731
• Nº de acceso UniProt: Q92731
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ESR2(2100)

Descripción

Descripción general

Estrogen Receptor-β (ERβ) is a member of the nuclear receptor superfamily. It has nine exons and is mapped to human chromosome 14q23.2.

Anti-Estrogen Receptor-β Antibody detects endogenous levels of total Estrogen Receptor-β protein.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta.

Immunogen Range: 71-120

Aplicación

Anti-Estrogen Receptor-βantibody has been used in western blotting .{42,43}

Acciones bioquímicas o fisiológicas

Estrogen Receptor-β (ERβ) is involved in immune and inflammatory response. In females, estrogen receptor β (ESR2) is expected to play an important role in the progress of MDD (major depressive disorder). Aberrations in ESR2 gene result in bone mineral density variation.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable