SAB4200742

Anti-c-Myc-Peroxidase antibody, Mouse monoclonal

clone 9E10, purified from hybridoma cell culture

• Sinónimos: Anti-MRTL, Anti-Myc, Anti-bHLHe39, Anti-v-myc avian myelocytomatosis viral oncogene homolog
• Código UNSPSC: 12352203
• NACRES: NA.56

Propiedades

• origen biológico: mouse
• Nivel de calidad: 200
• conjugado: peroxidase conjugate
• forma del anticuerpo: purified from hybridoma cell culture
• tipo de anticuerpo: primary antibodies
• clon: 9E10, monoclonal
• Formulario: lyophilized powder
• reactividad de especies: human
• envase: vial of 100 μL
• concentración: ~2 mg/mL
• técnicas: immunoblotting: 1:250-1:500 using lysate of HEK-293T cells over expressing c-Myc fusion protein; immunohistochemistry: suitable
• isotipo: IgG1
• Nº de acceso UniProt: P01106
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MYC(4609)

Descripción

Descripción general

Monoclonal Anti-c-Myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with synthetic peptide of the human p62c-myc protein, conjugated to KLH. c-Myc is a proto-oncogene localized on long arm of human chromosome 8. The encoded protein contains an N-terminal transactivation domain. The human c-Myc proto-oncogene is the cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses.

Especificidad

Monoclonal Anti-Calponin specifically recognizes smooth muscle Calponin.

Inmunógeno

Synthetic peptide of the human p62c-myc protein.

Aplicación

Anti-c-Myc-Peroxidase antibody, Mouse monoclonal may be used in immunoblotting and immunohistology.

Acciones bioquímicas o fisiológicas

c-Myc is a transcription factor involved in regulation of cell growth, proliferation, differentiation and apoptosis. It is implicated in DNA replication, RNA splicing or transcription. Increased expression of the gene is associated with the development of various types of human cancers.

Forma física

Supplied as lyophilized powder. After reconstitution with 0.1 mL of distilled water to a final antibody concentration of ∼ 2 mg/mL, the solution contains 1% BSA, 2.5% trehalose, 0.05% MIT in 0.01 M sodium phosphate buffered saline

Almacenamiento y estabilidad

Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable