S8251

Succinylcholine chloride dihydrate

98.0-102.0%, Cholinergic antagonist, solid

• Sinónimos: Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride
• Fórmula lineal: [(CH₃)₃NCH₂CH₂OCOCH₂]₂Cl₂ · 2H₂O
• Número CAS: 6101-15-1
• Peso molecular: 397.34
• NACRES: NA.77
• PubChem Substance ID: 24277873
• UNSPSC Code: 41116107
• EC Number: 200-747-4
• MDL number: MFCD00150564
• Beilstein/REAXYS Number: 3922827
• Assay: 98.0-102.0%
• Form: solid

Propiedades

• Nombre del producto: Succinylcholine chloride dihydrate, 98.0-102.0%, solid
• Quality Segment: 100
• assay: 98.0-102.0%
• form: solid
• color: white
• solubility: H₂O: complete 100 mg/ml, clear to slightly hazy, colorless, H₂O: soluble (unstable at pH > 9.)
• originator: Novartis
• SMILES string: O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
• InChI: 1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
• InChI key: FFSBEIRFVXGRPR-UHFFFAOYSA-L

Descripción

Application

Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.^4,5

Biochem/physiol Actions

Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.

Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.³

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Solutions may be stored for several days at 4 °C.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H301
• Indicaciones de precaución: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)