P9271

α-(4-Pyridyl N-oxide)-N-tert-butylnitrone

~95%

• Sinónimos: N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide, N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide, POBN
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂O₂
• Número CAS: 66893-81-0
• Peso molecular: 194.23
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24899024
• EC Number: 266-512-3
• Beilstein/REAXYS Number: 1453764
• MDL number: MFCD00041022
• Assay: ~95%
• Form: crystals

Propiedades

• assay: ~95%
• Quality Segment: 200
• form: crystals
• mp: 183-185 °C (lit.)
• functional group: amine
• storage temp.: room temp
• SMILES string: CC(C)(C)\[N+]([O-])=C/c1cc[n+]([O-])cc1
• InChI: 1S/C10H14N2O2/c1-10(2,3)12(14)8-9-4-6-11(13)7-5-9/h4-8H,1-3H3/b12-8+
• InChI key: RNRMWTCECDHNQU-XYOKQWHBSA-N

Descripción

Application

Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)