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P3657

Sigma-Aldrich

Pyridoxal 5′-phosphate hydrate

powder, BioReagent, suitable for cell culture

Sinónimos:

3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate

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About This Item

Fórmula empírica (notación de Hill):
C8H10NO6P · xH2O
Número de CAS:
853645-22-4
Peso molecular:
247.14 (anhydrous basis)
Beilstein:
234749
Número CE:
200-208-3
Número MDL:
MFCD00006333
Código UNSPSC:
12352205
ID de la sustancia en PubChem:
24898438
NACRES:
NA.75

Línea del producto

BioReagent

Nivel de calidad

200

Ensayo

≥98%

Formulario

powder

mol peso

Mw 247.14 g/mol

técnicas

cell culture | mammalian: suitable

color

off-white to yellow-brown

mp

140-143 °C

solubilidad

1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

temp. de almacenamiento

−20°C

cadena SMILES

CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI

1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

Clave InChI

NGVDGCNFYWLIFO-UHFFFAOYSA-N

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Descripción general

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Aplicación


  • Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5′-phosphate.: Discusses the development of advanced hemodialysis membranes using pyridoxal 5′-phosphate, highlighting its role in reducing homocysteine levels, which could contribute to improved outcomes for dialysis patients (Jiang P et al., 2020).

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Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
WXBF1702V
SLCL8133
SLCK7246
SLCD6819
SLBZ7499

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Ivone Carvalho et al.
Bioorganic & medicinal chemistry, 18(7), 2412-2427 (2010-03-26)
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of
Trina Das et al.
The Journal of general virology, 96(Pt 2), 294-310 (2014-10-30)
Chikungunya virus (CHIKV) has recently affected millions of people in the Indian Ocean, with rare cases of encephalopathy and encephalitis occurring in neonates. In the study described herein, the capacity of mouse brain cells to control infection through innate immune
Jennifer H Richens et al.
Biology open, 4(8), 1052-1061 (2015-07-15)
Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in
Bogdan F G Popescu et al.
Neurology, 84(2), 148-158 (2014-12-17)
To assess, in a surgical biopsy cohort of active demyelinating lesions, the diagnostic utility of aquaporin-4 (AQP4) immunohistochemistry in identifying neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD) and describe pathologic features that should prompt AQP4 immunohistochemical analysis and AQP4-immunoglobulin
Jun Araki et al.
Transplantation, 99(4), 687-692 (2015-01-22)
For managing major limb amputation, it is important to consider ischemic time and reperfusion injury by free radicals after the blood supply is reestablished. State of preservation during transplant surgery is crucial for the survival and function of the tissue
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Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

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Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

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