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N1887

Sigma-Aldrich

Neohesperidin

≥90% (HPLC)

Sinónimos:

(S)-4′-Methoxy-3′,5,7-trihydroxyflavanone-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranoside], Hesperetin 7-O-neohesperidoside, NSC 31048

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About This Item

Fórmula empírica (notación de Hill):
C28H34O15
Número de CAS:
13241-33-3
Peso molecular:
610.56
Beilstein/REAXYS Number:
74945
EC Number:
236-216-9
MDL number:
MFCD16661259
UNSPSC Code:
12352201
PubChem Substance ID:
24897534
NACRES:
NA.25

biological source

plant (orange)

assay

≥90% (HPLC)

form

powder

color

white to light brown

mp

245.3  °C ((473.5 °F ) at 1,011 hPa - OECD Test)

solubility

pyridine: 20 mg/mL, clear, faintly yellow to yellow

storage temp.

2-8°C

SMILES string

COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc3O2

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7,10,17,19,21-31,33-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1

InChI key

ARGKVCXINMKCAZ-UZRWAPQLSA-N

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General description

Neohesperidin is a flavonoid.

Application

Neohesperidin has been used in a study to assess the composition of shiikuwasha peels of different cultivation lines. It has also been used in a study to investigate the protective effects of an extract from Citrus bergamia against inflammatory injury.

Biochem/physiol Actions

Flavanone glycoside with neuroprotective and antioxidant properties. Does not inhibit oral carcinogenesis in a rat model unlike other citrus flavanones, but does exert a protective effect against gastritis and gastric lesions.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Neohesperidin dihydrochalcone analytical standard

Supelco

75041

Neohesperidin dihydrochalcone

Hesperidin analytical standard

Supelco

50162

Hesperidin

Naringin ≥90% (HPLC), from citrus fruit

Sigma-Aldrich

N1376

Naringin

(±)-Naringenin ≥95%

Sigma-Aldrich

N5893

(±)-Naringenin

Phloretin ≥99%

Sigma-Aldrich

P7912

Phloretin

Hesperetin ≥95%

Sigma-Aldrich

W431300

Hesperetin

Naringin analytical standard

Supelco

91842

Naringin

Adriana C E Graziano et al.
Life sciences, 90(25-26), 968-974 (2012-05-29)
The present work evaluated the anti-inflammatory/antioxidant activity of a well characterized extract from Citrus bergamia Risso and Poiteau (CBE), containing neoeriocitrin, naringin, neohesperidin and other flavonoids, on human NCTC 2544 keratinocytes treated with interferon-gamma (IFN-γ) and histamine (H). High performance
Agata Zygler et al.
Analytical and bioanalytical chemistry, 400(7), 2159-2172 (2011-04-06)
An analytical procedure involving solid-phase extraction (SPE) and high-performance liquid chromatography-mass spectrometry has been developed for the determination of nine high-intensity sweeteners authorised in the EU; acesulfame-K (ACS-K), aspartame (ASP), alitame (ALI), cyclamate (CYC), dulcin (DUL), neohesperidin dihydrochalcone (NHDC), neotame
B Aydeniz Güneşer et al.
Journal of food science and technology, 56(2), 634-642 (2019-03-25)
This study aims to report the composition of bioactives and volatile aromatic compounds, and determine the descriptive sensory properties of cold-pressed orange seed oil. The effects of oven pre-roasting and microwave pre-roasting of the seeds before cold pressing were compared.
Yonathan Asikin et al.
Journal of agricultural and food chemistry, 60(32), 7973-7980 (2012-07-19)
Citrus peels are important sources of various pleasant aroma compounds and valuable bioactive substances. To investigate differences in the composition and content of Shiikuwasha (Citrus depressa Hayata) peels from different cultivation lines, the composition of volatile aroma components, flavanones, and
Feng-Quan Tan et al.
BMC plant biology, 15, 89-89 (2015-04-08)
Polyploidy has often been considered to confer plants a better adaptation to environmental stresses. Tetraploid citrus rootstocks are expected to have stronger stress tolerance than diploid. Plenty of doubled diploid citrus plants were exploited from diploid species for citrus rootstock
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