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Merck

N0758

Sigma-Aldrich

Naphthol AS-D chloroacetate

esterase substrate, fluorogenic, ≥98% (TLC), powder

Sinónimos:

3-Hydroxy-2-naphthoic-o-toluidide chloroacetate

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About This Item

Fórmula empírica (notación de Hill):
C20H16ClNO3
Número de CAS:
Peso molecular:
353.80
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Naphthol AS-D chloroacetate, esterase substrate

assay

≥98% (TLC)

form

powder

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cc1ccccc1NC(=O)c2cc3ccccc3cc2OC(=O)CCl

InChI

1S/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)

InChI key

FMVKYSCWHDVMGO-UHFFFAOYSA-N

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Application

Naphthol AS-D chloroacetate has been in a substrate solution for naphthol-AS-D-chloroacetate-esterase (CIAE) staining.
Naphthol AS-D chloroacetate has been used as a component of the substrate solution for naphthol-AS-D-chloroacetate-esterase (CIAE) staining to detect:
  • the paraffin-embedded kidney tissues
  • polymorphonuclear (PMN) cells
  • endometrial tissues
  • neutrophils from mice small intestine

Substrates

Substrate for histochemical localization of esterases

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Muscarinic-acetylcholine-receptors (mAChRs) modulate intestinal homeostasis, but their role in inflammation is unclear; thus, this issue was the focus of this study. BALB/c mice were treated for 7 days with muscarine (mAChR/agonist), atropine (mAChR/antagonist) or saline. Small-intestine samples were collected for histology
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