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L2752

Sigma-Aldrich

Leu-Leu

>98% (TLC), suitable for ligand binding assays

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About This Item

Fórmula empírica (notación de Hill):
C12H24N2O3
Número de CAS:
3303-31-9
Peso molecular:
244.33
EC Number:
221-976-6
MDL number:
MFCD00065185
UNSPSC Code:
12352202
PubChem Substance ID:
24896323
NACRES:
NA.26

product name

Leu-Leu,

assay

>98% (TLC)

Quality Level

200

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

Storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI

1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1

Inchi Key

LCPYQJIKPJDLLB-UWVGGRQHSA-N

Categorías relacionadas

Amino Acid Sequence

Leu-Leu

Biochem/physiol Actions

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Guoqing Wang et al.
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Traditionally, hydrogen peroxide (H2O2) was formed from cellular oxidative metabolism and often viewed as toxic waste. In fact, H2O2 was a benefit messenger for neuron-glia signaling and synaptic transmission. Thus, H2O2 was a double-edged sword and neuroprotection vs. neurotoxicity produced
Lingling Zhang et al.
Oncogene, 39(49), 7196-7208 (2020-10-11)
Metastasis is responsible for the death of most breast cancer patients. Robo1 has been implicated as a tumor suppressor for various cancers including breast cancer. However, it is not well understood how Robo1 expression is regulated during tumorigenesis. In this
Yanzhen Zhou et al.
Journal of neuroinflammation, 15(1), 161-161 (2018-05-29)
Microglia-mediated neuroinflammation is recognized to mainly contribute to the pathogenesis of Parkinson's disease (PD). Tetrahydroxystilbene glucoside (TSG) has been proved to be beneficial for health with a great number of pharmacological properties. We examined the effects of TSG against dopamine
A van Boven et al.
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Different strains of Lactococcus lactis ssp. cremoris hydrolyze peptides at different rates while the cell-free extracts of these strains all show the same or much higher rates of hydrolysis. These observations indicate that the uptake of peptides is the rate-limiting
Anand Sitaram et al.
Molecular biology of the cell, 23(16), 3178-3192 (2012-06-22)
Cell types that generate unique lysosome-related organelles (LROs), such as melanosomes in melanocytes, populate nascent LROs with cargoes that are diverted from endosomes. Cargo sorting toward melanosomes correlates with binding via cytoplasmically exposed sorting signals to either heterotetrameric adaptor AP-1
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