G3796

Granisetron hydrochloride

≥98% (HPLC), solid

• Sinónimos: 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride
• Fórmula empírica (notación de Hill): C₁₈H₂₄N₄O· HCl
• Número de CAS: 107007-99-8
• Peso molecular: 348.87
• MDL number: MFCD01747034
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799917
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white to off-white
• mp: 284.0-290.0 °C
• solubility: H₂O: >10 mg/mL
• originator: Roche
• Storage temp.: room temp
• SMILES string: Cl.CN1[C@H]2CCC[C@@H]1C[C@@H](C2)NC(=O)c3nn(C)c4ccccc34
• InChI: 1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
• Inchi Key: QYZRTBKYBJRGJB-WQTKJZBYSA-N

Descripción

Biochem/physiol Actions

Granisetron hydrochloride helps to block nausea/emesis and abdominal pain in irritable bowel syndrome, that is stimulated by chemotherapy.

Granisetron hydrochloride is a serotonin 5-HT₃ receptor antagonist and antiemetic.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves