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C9538

Coenzyme Q10

≥98% (HPLC), powder, antioxidant

Sinónimos:

CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10

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Fórmula empírica (notación de Hill):
C59H90O4
Número CAS:
Peso molecular:
863.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-147-9
MDL number:
Beilstein/REAXYS Number:
1900141
Assay:
≥98% (HPLC)
Form:
powder
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Nombre del producto

Coenzyme Q10, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

yellow to dark orange

mp

49 °C

application(s)

cell analysis

storage temp.

−20°C

SMILES string

O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O

InChI

1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

InChI key

ACTIUHUUMQJHFO-UPTCCGCDSA-N

General description

Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria ([1]) which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health ([2]). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ([3] ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ([1])

Application

Coenzyme Q10 (CoQ10) has been used:
  • as a bioactive compound to study its immune modulating properties in vitro[4]
  • as a standard for high-performance liquid chromatography[5][6]
  • to study its effect on exercised rat aorta[7]
  • in the cellular CoQ uptake assay[8]

Biochem/physiol Actions

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.[5]

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Este artículo
07386V-060U0020001
assay

≥98% (HPLC)

assay

≥97.5% (HPLC)

assay

-

assay

-

form

powder

form

powder

form

liquid

form

solid

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

color

yellow to dark orange

color

faint yellow to dark orange

color

-

color

-

application(s)

cell analysis

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

clinical testing

application(s)

pharmaceutical (small molecule)


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. Regarding this product, C9538, can it be used as primary reference standard for the content determination of CoQ10?

    1 answer
    1. This product has not been tested for use as an analytical standard. There are currently three products available that qualify for use as a standard, under the name Ubidecarenone - 2 primary standards and 1 secondary standard. Please see the link below to review these product options:
      https://www.sigmaaldrich.com/US/en/substance/ubidecarenone86334303980

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