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C8912

Sigma-Aldrich

Cocaine free base

Sinónimos:

Ecgonine methyl ester benzoate

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About This Item

Fórmula empírica (notación de Hill):
C17H21NO4
Número de CAS:
50-36-2
Peso molecular:
303.35
EC Number:
200-032-7
MDL number:
MFCD00056906
UNSPSC Code:
12352200
PubChem Substance ID:
24893116
NACRES:
NA.77

form

powder

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

application(s)

forensics and toxicology

SMILES string

[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c3ccccc3)C(=O)OC)N2C

InChI

1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

InChI key

ZPUCINDJVBIVPJ-LJISPDSOSA-N

Gene Information

human ... DRD3(1814) , KCNH1(3756) , KCNH2(3757) , SCN10A(6336) , SCN11A(11280) , SCN5A(6331) , SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
mouse ... Slc6a2(20538)
rat ... Chrm1(25229) , Slc6a3(24898) , Slc6a4(25553)

Biochem/physiol Actions

Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análisis (COA)

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