C4284
β-Chloro-D-alanine hydrochloride
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About This Item
Fórmula lineal:
C3H6NO2Cl · HCl
Número de CAS:
Peso molecular:
160.00
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
Productos recomendados
assay
≥98% (TLC)
Quality Level
form
powder
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
storage temp.
−20°C
SMILES string
Cl.N[C@H](CCl)C(O)=O
InChI
1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m1./s1
InChI key
IENJPSDBNBGIEL-HSHFZTNMSA-N
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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J M Manning et al.
Proceedings of the National Academy of Sciences of the United States of America, 71(2), 417-421 (1974-02-01)
The D- and L-isomers of beta-chloroalanine inhibit the growth of Diplococcus pneumoniae, Streptococcus pyogenes, Bacillus subtilis, and Escherichia coli. With pneumococcus the inhibition by beta-chloro-D-alanine is completely prevented by either D-alanine or D-alanyl-D-alanine, while L-alanine is not effective in preventing
Yuki Ogasawara et al.
Journal of biochemical and biophysical methods, 51(2), 139-150 (2002-06-14)
A highly sensitive method has been developed for the determination of gamma-cystathionase (EC. 4.4.1.1.) activity in rat tissues using beta-chloro-L-alanine as a substrate. This method is based on colorimetry for the determination of pyruvate produced from beta-chloro-L-alanine with the beta-elimination
Jorge Cerbon et al.
Experimental parasitology, 122(2), 106-111 (2009-03-03)
The sphingolipids biosynthesis pathway generates bioactive molecules crucial to the regulation of physiological processes. We have recently reported that DAG (diacylglycerol) generated during sphingomyelin synthesis, plays an important role in PKC (protein kinase C) activation, necessary for the transit through
Arthur J L Cooper et al.
Biochemical pharmacology, 65(2), 181-192 (2002-12-31)
The mitochondrial and cytosolic branched-chain aminotransferases (BCAT(m) and BCAT(c)) are homodimers in the fold type IV class of pyridoxal 5'-phosphate-containing enzymes that also contains D-amino acid aminotransferase and 4-amino-4-deoxychorismate lyase (a beta-lyase). Recombinant human BCAT(m) and BCAT(c) were shown to
Agnieszka Robaszkiewicz et al.
Mechanisms of ageing and development, 129(10), 572-579 (2008-07-01)
The increase in the amount of oxidatively modified proteins is a hallmark of ageing and age-related disorders. This paper is aimed at a verification of the hypothesis that N-chloroamino acids, products of reaction between hypochlorite generated in vivo under pathological
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