A9451

Aristolochic acid I sodium salt

powder, ≥97%

• Sinónimos: Aristolochic acid sodium salt
• Fórmula empírica (notación de Hill): C₁₇H₁₀NNaO₇
• Número CAS: 10190-99-5
• Peso molecular: 363.25
• NACRES: NA.77
• PubChem Substance ID: 24891454
• UNSPSC Code: 12352202
• EC Number: 233-463-4
• MDL number: MFCD00210760
• Assay: ≥97%
• Form: powder
• Solubility: H₂O: 50 mg/mL

Propiedades

• Quality Segment: 200
• assay: ≥97%
• form: powder
• solubility: H₂O: 50 mg/mL
• SMILES string: [Na+].COc1cccc2c1cc([N+]([O-])=O)c3c(cc4OCOc4c23)C([O-])=O
• InChI: 1S/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1
• InChI key: BQVOPWJSBBMGBR-UHFFFAOYSA-M

Descripción

Biochem/physiol Actions

Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H351
• pcodes: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges