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Merck

A8604

Anti-Annexin V antibody, Mouse monoclonal

clone AN5, purified from hybridoma cell culture

Sinónimos:

Annexin V Antibody, Annexin V Antibody - Monoclonal Anti-Annexin V antibody produced in mouse

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
AN5, monoclonal
Application:
ARR, ELISA (i), ICC, WB
Citations:
10
Servicio técnico
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

AN5, monoclonal

form

buffered aqueous solution

mol wt

antigen ~35 kDa

species reactivity

human

technique(s)

immunocytochemistry: suitable, indirect ELISA: suitable, microarray: suitable, western blot: 0.5-1 μg/mL using HeLa total cell extract

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ANXA5(308)

General description

Monoclonal Anti-Annexin V (mouse IgG1 isotype) is derived from the hybridoma AN5 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice immunized with purified human Annexin V. Annexin V belongs to a class of Ca2+-dependent binding proteins. the amino acid sequence of the annexin V protein consists of a core of four repeats of a highly conserved 70 amino acid residue motif and a unique N-terminal tail. Within each repeat, there is a 17 amino acid residue consensus sequence, which is postulated to form part of the Ca2+ and/or phospholipid binding site.

Immunogen

purified human annexin V.

Application

Monoclonal Anti-Annexin V antibody produced in mouse has been used in:
  • immunocytochemistry
  • indirect immunofluorescence
  • immunohistochemistry
  • western blotting
  • enzyme linked immunosorbent assay (ELISA)

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Contenido relacionado


Domain IV of Annexin A5 Is Critical for Binding Calcium and Guarantees Its Maximum Binding to the Phosphatidylserine Membrane
Wang J, et al.
Molecules (Basel), 22(12), 2256-2256 (2017)
Expression of pro-and-anti-apoptotic antigens in the cerebellum of dogs naturally infected with canine distemper virus
Bregano LC, et al.
Brazilian Journal of Veterinary Pathology, 3(2), 16-16 (2010)
H Grassme et al.
The Journal of biological chemistry, 276(23), 20589-20596 (2001-03-30)
Clustering seems to be employed by many receptors for transmembrane signaling. Here, we show that acid sphingomyelinase (ASM)-released ceramide is essential for clustering of CD95. In vitro and in vivo, extracellularly orientated ceramide, released upon CD95-triggered translocation of ASM to



Número de artículo de comercio global

SKUGTIN
A8604-100UL04061833400388
A8604-200UL04061838102393